Hairy cell leukemia. Never in nodes. BLOOD: mimics aplastic anemia (has characteristic MONOCYTOPENIA and neutropenia- reason you would die from it). Very few neoplastic cells in blood. DO NOT DIAGNOSE if there are monocytes. Classic cell morphology = bigger, with nucleus 2x size of normal one and the cell size is very uniform, no transformed cells. Nuclei can be round, oval, RENIFORM, or bilobed. Chromatin is very distinct ground glass and NO by carolina
carolina
carolina Hairy cell leukemia. Never in nodes. BLOOD: mimics aplastic anemia (has characteristic MONOCYTOPENIA and neutropenia- reason you would die from it). Very few neoplastic cells in blood. DO NOT DIAGNOSE if there are monocytes. Classic cell morphology = bigger, with nucleus 2x size of normal one and the cell size is very uniform, no transformed cells. Nuclei can be round, oval, RENIFORM, or bilobed. Chromatin is very distinct ground glass and NO
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Ruptured venule. Coloured scanning electron micrograph (SEM) showing stacks (rouleaux) of red blood cells exposed inside a torn venule. A venule is a very small blood vessel in the microcirculation that allows deoxygenated blood to return from the capillary beds to the larger blood vessels (veins). Red blood cells are the most abundant cell in the blood. They have no nucleus and are about 7 micrometers across. Magnification: x2300 when printed at 10 centimetres wide. by shopportunity
shopportunity
shopportunity Ruptured venule. Coloured scanning electron micrograph (SEM) showing stacks (rouleaux) of red blood cells exposed inside a torn venule. A venule is a very small blood vessel in the microcirculation that allows deoxygenated blood to return from the capillary beds to the larger blood vessels (veins). Red blood cells are the most abundant cell in the blood. They have no nucleus and are about 7 micrometers across. Magnification: x2300 when printed at 10 centimetres wide.
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Normal body-type gastric mucosa. Autoimmune chronic atrophic gastritis is restricted to body (not antrum). Antiparietal cell antibodies and anti-IF antibodies, +/- pernicious anemia. Destroy acid-producing parietal cells, leading to achlorhydria, which in turn stimulates gastrin leading to hypergastrinemia and ulcers. by graciela
graciela
graciela Normal body-type gastric mucosa. Autoimmune chronic atrophic gastritis is restricted to body (not antrum). Antiparietal cell antibodies and anti-IF antibodies, +/- pernicious anemia. Destroy acid-producing parietal cells, leading to achlorhydria, which in turn stimulates gastrin leading to hypergastrinemia and ulcers.
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B cell defects.  1. Bruton (X-linked), recurrent pyogenic, males, 6 months. GIARDIA. No plasma cells in GI biopsies. Very low serum IgG. Normal immunity to viral and fungal, increased risk of lymphomas. Atk gene (Tyrosine kinase). 2. CVID low overall serum Ig of every class and some T cell issues too. RESPIRATORY TRACT, Giardia, bronchiectasis. Normal number of B cells but cannot differentiate into plasma cells. 3. Selective IgA. 4. Job (hyper by jackie
jackie
jackie B cell defects. 1. Bruton (X-linked), recurrent pyogenic, males, 6 months. GIARDIA. No plasma cells in GI biopsies. Very low serum IgG. Normal immunity to viral and fungal, increased risk of lymphomas. Atk gene (Tyrosine kinase). 2. CVID low overall serum Ig of every class and some T cell issues too. RESPIRATORY TRACT, Giardia, bronchiectasis. Normal number of B cells but cannot differentiate into plasma cells. 3. Selective IgA. 4. Job (hyper
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PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei. by tamera
tamera
tamera PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei.
Nobody Does it Better than Nature
Scrotum. Granular cell tumor. S100 positive, CD68 positive, inhibin positive. Lysosomes on EM. uvenile xanthogranuloma features histiocytic cells which merge with those with features of Touton-like giant cells. This lesion labels for CD68, but not for S100 or CD1a. Langerhans histiocytosis is composed of cells with more reniform nuclei, and the lesional cells label for CD1a. by carolina
carolina
carolina Scrotum. Granular cell tumor. S100 positive, CD68 positive, inhibin positive. Lysosomes on EM. uvenile xanthogranuloma features histiocytic cells which merge with those with features of Touton-like giant cells. This lesion labels for CD68, but not for S100 or CD1a. Langerhans histiocytosis is composed of cells with more reniform nuclei, and the lesional cells label for CD1a.
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Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini
Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam)
Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm)
Signet ring cells or intercellular glandular lumens by rochelle
rochelle
rochelle Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam) Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm) Signet ring cells or intercellular glandular lumens
bargain
CLL/SLL. Smudge cells (EDTA), usually <30K, prolymphs <10%. BM is commonly involved at presentation- nodular (better), diffuse (worse prognosis) or interstitial.  IHC: CD19, CD20 DIM**, CD5 and CD23 (also 79, 22, 43, and 11c). Negative for FMC-7, 10, bcl1 and bcl6. bcl2 expressed in all B cell neoplasms pretty much. CD38 and/or ZAP-70 = UNMUTATED and WORSE prognosis. (An increase in polyclonal lymphs that coexpress CD5 and CD19 is sometimes seen in RA, HCV and post-BMT). Deletion13q14 is most common and is best prognosis (Trisomy 12 is intermediate). Bad ones are del11 and del 17. Transformation to PLL (11-55%) is heralded by weaker 5 and 23, stronger 20. PROGNOSIS = Rai and Binet staging.  Worse if you have B symptoms, HSM, anemia or thromboytopenia, high doubling time, atypical morphology. by nettie
nettie
nettie CLL/SLL. Smudge cells (EDTA), usually <30K, prolymphs <10%. BM is commonly involved at presentation- nodular (better), diffuse (worse prognosis) or interstitial. IHC: CD19, CD20 DIM**, CD5 and CD23 (also 79, 22, 43, and 11c). Negative for FMC-7, 10, bcl1 and bcl6. bcl2 expressed in all B cell neoplasms pretty much. CD38 and/or ZAP-70 = UNMUTATED and WORSE prognosis. (An increase in polyclonal lymphs that coexpress CD5 and CD19 is sometimes seen in RA, HCV and post-BMT). Deletion13q14 is most common and is best prognosis (Trisomy 12 is intermediate). Bad ones are del11 and del 17. Transformation to PLL (11-55%) is heralded by weaker 5 and 23, stronger 20. PROGNOSIS = Rai and Binet staging. Worse if you have B symptoms, HSM, anemia or thromboytopenia, high doubling time, atypical morphology.
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"A water break? Water is for cowards. Water makes you weak. Water is for washing blood off that uniform and you don't get no blood on my uniform!" by rita
rita
rita "A water break? Water is for cowards. Water makes you weak. Water is for washing blood off that uniform and you don't get no blood on my uniform!"
For the Home
Lung cells. Immunofluorescence light micrograph of pulmonary endothelial cells. Endothelial cells are specialized epithelial cells that line the inner surface of blood vessels. Nuclei, which contain the cell's genetic information, are purple; actin filaments, which are major components of the cytoskeleton, are cyan; mitochondria, which generate energy for the cell, are white. © Dr. Torsten Wittmann / Science Source #lungcells #pulmonary #micrograph #sciencephotos #stockimages #sciencesource by katharine
katharine
katharine Lung cells. Immunofluorescence light micrograph of pulmonary endothelial cells. Endothelial cells are specialized epithelial cells that line the inner surface of blood vessels. Nuclei, which contain the cell's genetic information, are purple; actin filaments, which are major components of the cytoskeleton, are cyan; mitochondria, which generate energy for the cell, are white. © Dr. Torsten Wittmann / Science Source #lungcells #pulmonary #micrograph #sciencephotos #stockimages #sciencesource
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MONOCYTOPENIA = hairy cell leukemia.  It also heralds the onset of neutropenia in chemo. by eloise
eloise
eloise MONOCYTOPENIA = hairy cell leukemia. It also heralds the onset of neutropenia in chemo.
Hairz
red and white blood cells by concetta
concetta
concetta red and white blood cells
Cowboy theme party.
"Thalassemic Indices" = ELEVATED RBC, low MCV, low Hct, and normal RDW.  If the degree of anemia doesn't quite fit with the microcytosis, think of thalassemia (vs. IDA in which the anemia and microcytosis do fit).  Smear shows occ target cells and BASOPHILIC stippling. by robbie
robbie
robbie "Thalassemic Indices" = ELEVATED RBC, low MCV, low Hct, and normal RDW. If the degree of anemia doesn't quite fit with the microcytosis, think of thalassemia (vs. IDA in which the anemia and microcytosis do fit). Smear shows occ target cells and BASOPHILIC stippling.
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Adenocarcinoma. The cell in focus is comprised of a large nucleus, promininent nucleoli with an eccentric cytoplasm, suggesting glandular differentiation. Another fragment is shown with cells in a cohesive group with subtle cell borders. The nuclear outlines are irregular, and each contains a prominent nucleoli. The degree of atypia is consistent with an adenocarcinoma. The clean smear background is suggestive of a metastasis. by brittney
brittney
brittney Adenocarcinoma. The cell in focus is comprised of a large nucleus, promininent nucleoli with an eccentric cytoplasm, suggesting glandular differentiation. Another fragment is shown with cells in a cohesive group with subtle cell borders. The nuclear outlines are irregular, and each contains a prominent nucleoli. The degree of atypia is consistent with an adenocarcinoma. The clean smear background is suggestive of a metastasis.
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Hepatoblastoma. Three cell types. undifferentiated (small cells reminiscent of neuroblastoma or Wilms tumor), embryonal cells (slightly more mature cells with large nuclei, scant cytoplasm, arranged in some architectural pattern), and fetal cells (larger cells with abundant cytoplasm, smaller than mature hepatocytes). by marcie
marcie
marcie Hepatoblastoma. Three cell types. undifferentiated (small cells reminiscent of neuroblastoma or Wilms tumor), embryonal cells (slightly more mature cells with large nuclei, scant cytoplasm, arranged in some architectural pattern), and fetal cells (larger cells with abundant cytoplasm, smaller than mature hepatocytes).
For me?
Echinocytes (aka burr cells) in a peripheral blood smear. Note the uniform distribution of projections on the surface of the cell. Not to be confused with spur cells. Seen in chronic renal failure. by carolina
carolina
carolina Echinocytes (aka burr cells) in a peripheral blood smear. Note the uniform distribution of projections on the surface of the cell. Not to be confused with spur cells. Seen in chronic renal failure.
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Blood Cells by concetta
blood cells by enman
enman
enman blood cells
Biology
blood cells by concetta
HbC disease beta6glu--> lys).  CA is 40-50% in C band (A2 and C). Asymptomatic, may have target cells. CC is 90% C, 7% F, 3% A2 and NO A. Mild hemolytic anemia, splenomeg, and many targets!  Also have these rod shaped crystals, esp after splenectomy. by graciela
graciela
graciela HbC disease beta6glu--> lys). CA is 40-50% in C band (A2 and C). Asymptomatic, may have target cells. CC is 90% C, 7% F, 3% A2 and NO A. Mild hemolytic anemia, splenomeg, and many targets! Also have these rod shaped crystals, esp after splenectomy.
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Coriander (Cilantro) is considered both an herb & a spice since both its leaves and its seeds are used as a condiment. Some of the acids present in coriander, including ascorbic acid are very effective in reducing the cholesterol level in the blood while reducing the cholesterol deposition along the inner walls of the arteries & veins. Other benefits include anemia, swellings & digestion. #dherbs #healthtips by R&M
R&M
R&M Coriander (Cilantro) is considered both an herb & a spice since both its leaves and its seeds are used as a condiment. Some of the acids present in coriander, including ascorbic acid are very effective in reducing the cholesterol level in the blood while reducing the cholesterol deposition along the inner walls of the arteries & veins. Other benefits include anemia, swellings & digestion. #dherbs #healthtips
Hmmm
Understanding Sleep Apnea Infographic - I have sleep apnea and when first diagnosed I wouldn't wear my c-pap machine at night like I was supposed to. Over a period of a year my red and white blood cell counts increased to way above abnormal. They thought I might have leukemia. Come to find out it was just lack of oxygen to my cells from not wearing my c-pap at night. I was slowly killing myself. Now I wear it every night! by maryfair177
maryfair177
maryfair177 Understanding Sleep Apnea Infographic - I have sleep apnea and when first diagnosed I wouldn't wear my c-pap machine at night like I was supposed to. Over a period of a year my red and white blood cell counts increased to way above abnormal. They thought I might have leukemia. Come to find out it was just lack of oxygen to my cells from not wearing my c-pap at night. I was slowly killing myself. Now I wear it every night!
thingszs
Clinique Turnaround Revitalizing Serum is a high-powered serum that optimizes cell renewal to continually reveal fresher, healthier-looking skin. The oil-free formula helps bring vibrant new cells to the surface for a refined, uniform texture and $64.50 by nordstrom
nordstrom
nordstrom Clinique Turnaround Revitalizing Serum is a high-powered serum that optimizes cell renewal to continually reveal fresher, healthier-looking skin. The oil-free formula helps bring vibrant new cells to the surface for a refined, uniform texture and $64.50
Women
Scientists Find Ginger Kills Leukemia Cells and Shrinks Tumors in Vivo by ashleyw
ashleyw
ashleyw Scientists Find Ginger Kills Leukemia Cells and Shrinks Tumors in Vivo
My Favorite People
Human blood cells, coloured scanning electron micrograph (SEM). Seen here are platelets (small, roundish) and a neutrophil white blood cell (large, whitish). by JustLinnea
JustLinnea
JustLinnea Human blood cells, coloured scanning electron micrograph (SEM). Seen here are platelets (small, roundish) and a neutrophil white blood cell (large, whitish).
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Fixing uneven joins when you are welding letters together. You just need to adjust a few nodes and it is really pretty easy to do.    (EDIT POINTS) by luisa
luisa
luisa Fixing uneven joins when you are welding letters together. You just need to adjust a few nodes and it is really pretty easy to do. (EDIT POINTS)
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Migrating cancer cell. Coloured scanning electron micrograph (SEM) of a cultured cancer cell moving (metastasising) through a hole in a support film. Numerous pseudopodia (arm-like), fillipodia (thread-like) and surface blebs (lumps) can be seen. These features are characteristic of highly mobile cells, and enable cancerous cells to spread rapidly around the body, and invade other organs and tissues (metastasis). by LiveLoveLaughMyLife
LiveLoveLaughMyLife
LiveLoveLaughMyLife Migrating cancer cell. Coloured scanning electron micrograph (SEM) of a cultured cancer cell moving (metastasising) through a hole in a support film. Numerous pseudopodia (arm-like), fillipodia (thread-like) and surface blebs (lumps) can be seen. These features are characteristic of highly mobile cells, and enable cancerous cells to spread rapidly around the body, and invade other organs and tissues (metastasis).
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Thanks to a few tricks and a secret ingredient, this #beetroot #hummus is super #smooth despite no added oil and a very average blender. by ZaraFee
ZaraFee
ZaraFee Thanks to a few tricks and a secret ingredient, this #beetroot #hummus is super #smooth despite no added oil and a very average blender.
Vegetarian
This guy is awesome!! Very easy to understand. Paul Andersen takes you on a tour of the cell. He starts by explaining the difference between prokaryotic and eukaryotic cells. He also explains why cells are small but not infinitely small. He also explains how the organelles work together in a similar fashion. Intro Music Atribution Title: I4dsong_loop_main.wav Artist: CosmicD Link to soun... by socorro
socorro
socorro This guy is awesome!! Very easy to understand. Paul Andersen takes you on a tour of the cell. He starts by explaining the difference between prokaryotic and eukaryotic cells. He also explains why cells are small but not infinitely small. He also explains how the organelles work together in a similar fashion. Intro Music Atribution Title: I4dsong_loop_main.wav Artist: CosmicD Link to soun...
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There is so much truth in this. Big girls are so soft and feminine too. I know this guy loves that. Feels very secure and safe in a bigger woman's arms and being next to her curvy large soft body. Just love cuddling with my wife for this very reason. :-) by rosanna
rosanna
rosanna There is so much truth in this. Big girls are so soft and feminine too. I know this guy loves that. Feels very secure and safe in a bigger woman's arms and being next to her curvy large soft body. Just love cuddling with my wife for this very reason. :-)
Quotes
red blood cells by Chloé
Chloé
Chloé red blood cells
FUN