Marginal zone lymphomas. 1. Nodal = proliferation of monocyoid B cells in a diffuse, sinusoidal or interfollicular pattern, permeates the follicles.  Look for Dutcher bodies (ND- nuclear). 2. MALT = small round lymphs with lots of pale cytoplasm and indented nuclei (monocytoid B cells), plasma cells (ND), and lymphoepithelial lesions. The plasma cells are actually monoclonal!  Also can see regular old reactive follicles, don't be fooled that by dee
dee
dee Marginal zone lymphomas. 1. Nodal = proliferation of monocyoid B cells in a diffuse, sinusoidal or interfollicular pattern, permeates the follicles. Look for Dutcher bodies (ND- nuclear). 2. MALT = small round lymphs with lots of pale cytoplasm and indented nuclei (monocytoid B cells), plasma cells (ND), and lymphoepithelial lesions. The plasma cells are actually monoclonal! Also can see regular old reactive follicles, don't be fooled that
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YOUNG FEMALE SMOKERS = syndrome of persistent polyclonal B lymphocytosis. Mild abs lymphocytosis, with indented to bilobed nuclei and abundant pale staining cytoplasm.  Polyclonal IgM. HLA-DR7. by dee
dee
dee YOUNG FEMALE SMOKERS = syndrome of persistent polyclonal B lymphocytosis. Mild abs lymphocytosis, with indented to bilobed nuclei and abundant pale staining cytoplasm. Polyclonal IgM. HLA-DR7.
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Xp11 translocation renal cell carcinoma, 18 year old female. This tumor is composed of clear cells with abundant cytoplasm. The architecture is both papillary and nested. Psammoma bodies were found elsewhere. Given a tumor with both clear cells and papillary architecture in a patient of this young age, Xp11 Translocation Carcinoma becomes a serious diagnostic consideration. The diagnosis is confirmed by immunohistochemistry, revealing nuclear labeling for TFE3 protein. by maxine
maxine
maxine Xp11 translocation renal cell carcinoma, 18 year old female. This tumor is composed of clear cells with abundant cytoplasm. The architecture is both papillary and nested. Psammoma bodies were found elsewhere. Given a tumor with both clear cells and papillary architecture in a patient of this young age, Xp11 Translocation Carcinoma becomes a serious diagnostic consideration. The diagnosis is confirmed by immunohistochemistry, revealing nuclear labeling for TFE3 protein.
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Ewing/PNET. Calf of 11 year old boy.  Some of these cells form rosette-like structures. At high power, the lesion comprises of fairly monotonous, small round blue cells with scant cytoplasm, high N:C ratio, and multiple cytoplasmic vacuoles. The Papanicolaou-stained material demonstrates round to oval nuclei with multiple small nucleoli and occasional mitotic figures. Immunohistochemistry shows that the cells are immunoreactive for CD99 by graciela
graciela
graciela Ewing/PNET. Calf of 11 year old boy. Some of these cells form rosette-like structures. At high power, the lesion comprises of fairly monotonous, small round blue cells with scant cytoplasm, high N:C ratio, and multiple cytoplasmic vacuoles. The Papanicolaou-stained material demonstrates round to oval nuclei with multiple small nucleoli and occasional mitotic figures. Immunohistochemistry shows that the cells are immunoreactive for CD99
Spend
Creola bodies = groups of reactive bronchial cells with cilia on the outside. Do not mistake for cancer. by samanthasam
samanthasam
samanthasam Creola bodies = groups of reactive bronchial cells with cilia on the outside. Do not mistake for cancer.
amazing places and spaces
I like Gregg's! They gave yummy sausage rolls. Lots and lots of yummy foods you don't see here in the States, like beef and chicken pasties. by wendy
wendy
wendy I like Gregg's! They gave yummy sausage rolls. Lots and lots of yummy foods you don't see here in the States, like beef and chicken pasties.
words to live by.
Neuroblastoma, thoracic mass, 11 month old girl. This tumor differs from PNET in that neuroblastoma cells are variable in size, there is extensive neuropil, and focal ganglion cell differentiation may be seen in the form of cells with an amphophyllic cytoplasm and prominent nucleoli. The cells in PNET would be CD99 positive where as neuroblastoma cells would not. “neuroblastoma, stroma poor, poorly differentiated and low MKI by kim
kim
kim Neuroblastoma, thoracic mass, 11 month old girl. This tumor differs from PNET in that neuroblastoma cells are variable in size, there is extensive neuropil, and focal ganglion cell differentiation may be seen in the form of cells with an amphophyllic cytoplasm and prominent nucleoli. The cells in PNET would be CD99 positive where as neuroblastoma cells would not. “neuroblastoma, stroma poor, poorly differentiated and low MKI
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Explains the height.<<Very probable. The gods recognized him and staying hidden probably meant not attracting attention by body hopping on a regular basis. Also it's hard for archangels to get suitable bodies so they would have noticed lots of THOSE vessels going missing. by debbie
debbie
debbie Explains the height.<<Very probable. The gods recognized him and staying hidden probably meant not attracting attention by body hopping on a regular basis. Also it's hard for archangels to get suitable bodies so they would have noticed lots of THOSE vessels going missing.
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B cell defects.  1. Bruton (X-linked), recurrent pyogenic, males, 6 months. GIARDIA. No plasma cells in GI biopsies. Very low serum IgG. Normal immunity to viral and fungal, increased risk of lymphomas. Atk gene (Tyrosine kinase). 2. CVID low overall serum Ig of every class and some T cell issues too. RESPIRATORY TRACT, Giardia, bronchiectasis. Normal number of B cells but cannot differentiate into plasma cells. 3. Selective IgA. 4. Job (hyper by jackie
jackie
jackie B cell defects. 1. Bruton (X-linked), recurrent pyogenic, males, 6 months. GIARDIA. No plasma cells in GI biopsies. Very low serum IgG. Normal immunity to viral and fungal, increased risk of lymphomas. Atk gene (Tyrosine kinase). 2. CVID low overall serum Ig of every class and some T cell issues too. RESPIRATORY TRACT, Giardia, bronchiectasis. Normal number of B cells but cannot differentiate into plasma cells. 3. Selective IgA. 4. Job (hyper
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Lung cells. Immunofluorescence light micrograph of pulmonary endothelial cells. Endothelial cells are specialized epithelial cells that line the inner surface of blood vessels. Nuclei, which contain the cell's genetic information, are purple; actin filaments, which are major components of the cytoskeleton, are cyan; mitochondria, which generate energy for the cell, are white. © Dr. Torsten Wittmann / Science Source #lungcells #pulmonary #micrograph #sciencephotos #stockimages #sciencesource by katharine
katharine
katharine Lung cells. Immunofluorescence light micrograph of pulmonary endothelial cells. Endothelial cells are specialized epithelial cells that line the inner surface of blood vessels. Nuclei, which contain the cell's genetic information, are purple; actin filaments, which are major components of the cytoskeleton, are cyan; mitochondria, which generate energy for the cell, are white. © Dr. Torsten Wittmann / Science Source #lungcells #pulmonary #micrograph #sciencephotos #stockimages #sciencesource
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Acne is a skin disorder that occurs when the hair follicles become plugged with oil, dirt and dead skin cells. It appears commonly on face, neck, chest, back and shoulders. Depending on the severity it can cause emotional distress and then it can lead to scars of the skin. Apple cider vinegar is a powerhouse … by SandeM
SandeM
SandeM Acne is a skin disorder that occurs when the hair follicles become plugged with oil, dirt and dead skin cells. It appears commonly on face, neck, chest, back and shoulders. Depending on the severity it can cause emotional distress and then it can lead to scars of the skin. Apple cider vinegar is a powerhouse …
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Scrotum. Granular cell tumor. S100 positive, CD68 positive, inhibin positive. Lysosomes on EM. uvenile xanthogranuloma features histiocytic cells which merge with those with features of Touton-like giant cells. This lesion labels for CD68, but not for S100 or CD1a. Langerhans histiocytosis is composed of cells with more reniform nuclei, and the lesional cells label for CD1a. by carolina
carolina
carolina Scrotum. Granular cell tumor. S100 positive, CD68 positive, inhibin positive. Lysosomes on EM. uvenile xanthogranuloma features histiocytic cells which merge with those with features of Touton-like giant cells. This lesion labels for CD68, but not for S100 or CD1a. Langerhans histiocytosis is composed of cells with more reniform nuclei, and the lesional cells label for CD1a.
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Paint old furniture. Also, lots of things in this house are cool. Justina Blakeney: TOUR THE JUNGALOW by allisonn
allisonn
allisonn Paint old furniture. Also, lots of things in this house are cool. Justina Blakeney: TOUR THE JUNGALOW
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Cells for kids-- lots of links by beatrice
beatrice
beatrice Cells for kids-- lots of links
Halloweenie
Thanks to research from the University of Michigan and nearly three centuries of medicinal use, we can now utilize ginger root to not only kill ovarian cancer cells, but also prostate cancer cells with zero toxicity by AislingH
AislingH
AislingH Thanks to research from the University of Michigan and nearly three centuries of medicinal use, we can now utilize ginger root to not only kill ovarian cancer cells, but also prostate cancer cells with zero toxicity
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Quick and Easy School Lunch Ideas - lots of easy and different options that will actually survive the trip to school by alexis
alexis
alexis Quick and Easy School Lunch Ideas - lots of easy and different options that will actually survive the trip to school
For my kids
Don't be fooled. by lorimarie.biz
lorimarie.biz
lorimarie.biz Don't be fooled.
Sayings
#summer #outfits Don't Think I'll Ever Get Enough Of This Pretty Top It Also Comes In The Prettiest Pale Blue! I've Also Linked Dupes For My Sandals! by roslyn
roslyn
roslyn #summer #outfits Don't Think I'll Ever Get Enough Of This Pretty Top It Also Comes In The Prettiest Pale Blue! I've Also Linked Dupes For My Sandals!
Gear
MANTLE CELL LYMPHOMA. IRREGULAR nuclear contour and small delicate nucleolus. Diffuse to vaguely nodular. Admixed histiocytes in sheets and aggregates. Not usually in the blood. Blastoid variant.  IHC: 20 BRIGHT, CD5 pos and FMC-7 pos. sIg BRIGHT, CYCLIN D1. Neg for 23 and 11c. lambda restricted usually! t(11;14) = IgH and CCND1. Most have other abbereations, too. FISH detects 100% of the t(11;14) and is the test of choice. AGGRESSIVE clinical course (3-4 years). by dee
dee
dee MANTLE CELL LYMPHOMA. IRREGULAR nuclear contour and small delicate nucleolus. Diffuse to vaguely nodular. Admixed histiocytes in sheets and aggregates. Not usually in the blood. Blastoid variant. IHC: 20 BRIGHT, CD5 pos and FMC-7 pos. sIg BRIGHT, CYCLIN D1. Neg for 23 and 11c. lambda restricted usually! t(11;14) = IgH and CCND1. Most have other abbereations, too. FISH detects 100% of the t(11;14) and is the test of choice. AGGRESSIVE clinical course (3-4 years).
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PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei. by tamera
tamera
tamera PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei.
Nobody Does it Better than Nature
Fluoride is associated with cancer and it also accumulates in the thyroid as well as the pineal gland. The regular use of iodine will go a very long way toward mitigating the damages done in our bodies by the fluoride. by melody
melody
melody Fluoride is associated with cancer and it also accumulates in the thyroid as well as the pineal gland. The regular use of iodine will go a very long way toward mitigating the damages done in our bodies by the fluoride.
Yummy Recipes
Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini
Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam)
Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm)
Signet ring cells or intercellular glandular lumens by rochelle
rochelle
rochelle Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam) Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm) Signet ring cells or intercellular glandular lumens
bargain
Andy Warhol shows his scars - he was shot on June 3, 1968 by Valerie Solanas, the author of the SCUM Manifesto, a separatist attack on men and a marginal member of Warhol's Factory group. Andy barely survived and suffered physical effects for the rest of his life. Art critic Mario Amaya was also shot in the incident and suffered minor injuries. by azure angel
azure angel
azure angel Andy Warhol shows his scars - he was shot on June 3, 1968 by Valerie Solanas, the author of the SCUM Manifesto, a separatist attack on men and a marginal member of Warhol's Factory group. Andy barely survived and suffered physical effects for the rest of his life. Art critic Mario Amaya was also shot in the incident and suffered minor injuries.
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Okay, I usually dislike tattoos and don't see the point in them. But this one...this one I would actually do. by bridgette.jons
bridgette.jons
bridgette.jons Okay, I usually dislike tattoos and don't see the point in them. But this one...this one I would actually do.
Summer Fun
Detox your scalp using this DIY activated charcoal scalp treatment! Activated charcoal is a popular natural beauty ingredient nowadays. It’s praised for its incredible detoxifying effects! It sucks out all kinds of gunk in the hair follicles, like grime, dead cells, stale oils, pollution, dandruff and even toxins. This leaves your scalp & hair follicles … #scalpdetoxdiy #scalpdetoxfordandruff by elinor
elinor
elinor Detox your scalp using this DIY activated charcoal scalp treatment! Activated charcoal is a popular natural beauty ingredient nowadays. It’s praised for its incredible detoxifying effects! It sucks out all kinds of gunk in the hair follicles, like grime, dead cells, stale oils, pollution, dandruff and even toxins. This leaves your scalp & hair follicles … #scalpdetoxdiy #scalpdetoxfordandruff
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The Lesson Plan Diva: Landforms and Bodies of Water FREEBIE! by corrine
corrine
corrine The Lesson Plan Diva: Landforms and Bodies of Water FREEBIE!
Color Studies
DIY – Tension rods to hold & organize shoes | PinLog..... HMMMMM.... don't have the tension rods but have LOTS of regular curtain rods.... I have an idea!!!...... ;) by aftr
aftr
aftr DIY – Tension rods to hold & organize shoes | PinLog..... HMMMMM.... don't have the tension rods but have LOTS of regular curtain rods.... I have an idea!!!...... ;)
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Jojoba Oil – Jojoba oil is capable of moisturizing the follicles of hair and hence can make hair strands stronger & healthier. Jojoba also hydrates hair from th by BaileyJo93
BaileyJo93
BaileyJo93 Jojoba Oil – Jojoba oil is capable of moisturizing the follicles of hair and hence can make hair strands stronger & healthier. Jojoba also hydrates hair from th
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Types of AV Nodal Block by amberjane123
amberjane123
amberjane123 Types of AV Nodal Block
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Misoyaki Roast Chicken with Shoyu Onion Sauce; Red miso and mirin marinate permeates the bird and gives it the savory skin. The sauce of by francine
francine
francine Misoyaki Roast Chicken with Shoyu Onion Sauce; Red miso and mirin marinate permeates the bird and gives it the savory skin. The sauce of
Delicious
3D bio-printing: Cornell doctors and engineers built a lifelike artificial ear made of living cells using 3D printing technologies! Kids born with underdeveloped outer ears from congenital defects like microtia now have an opportunity to have an ear created from the tissues of their own bodies versus an artificial ear created from synthetic materials. One of the Cornell team’s prosthetic ears, created from living cartilage cells. Image via PLOS by tracy sam
tracy sam
tracy sam 3D bio-printing: Cornell doctors and engineers built a lifelike artificial ear made of living cells using 3D printing technologies! Kids born with underdeveloped outer ears from congenital defects like microtia now have an opportunity to have an ear created from the tissues of their own bodies versus an artificial ear created from synthetic materials. One of the Cornell team’s prosthetic ears, created from living cartilage cells. Image via PLOS
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