DARIER's Disease = This solitary keratotic papule has a somewhat endophytic growth pattern, with a central plug of keratin. There is both acantholysis and dyskeratosis. There is suprabasal acantholysis over a papillomatous superficial dermis. Above the suprabasal acantholysis, there are large, eosinophilic, rounded suprabasal cells with perinuclear halos (Corps Ronds). Above these are small dark cells with pyknotic nuclei and a millet-seed-like
Epithelioid sarcoma. The tumor lesion on low power has the morphology of a palisaded necrotizing granuloma. There appears to be central collagenous necrobiosis, and the lesional cells simulate histiocytes surrounding this necrobiosis. However, the surrounding cells demonstrate fairly prominent nucleoli, and mitotic figures are evident. These cells label for both cytokeratin (shown below) and CD34, establishing the diagnosis of epithelioid sarcoma.
Hairy cell leukemia. Never in nodes. BLOOD: mimics aplastic anemia (has characteristic MONOCYTOPENIA and neutropenia- reason you would die from it). Very few neoplastic cells in blood. DO NOT DIAGNOSE if there are monocytes. Classic cell morphology = bigger, with nucleus 2x size of normal one and the cell size is very uniform, no transformed cells. Nuclei can be round, oval, RENIFORM, or bilobed. Chromatin is very distinct ground glass and NO
Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini
Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam)
Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm)
Signet ring cells or intercellular glandular lumens
Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it difficult to breathe. There are two main forms of COPD: Chronic bronchitis, which involves a long-term cough with mucus Emphysema, which involves destruction of the lungs over time Most people with COPD have a combination of both conditions.
Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing. These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator into thinking it is actually a large predatory owl.
canalicular adenoma on lip. it is characterized by double columns of cells forming interconnecting channels that course through a loose myxoid stroma. The cells forming the channels have columnar, uniformly aligned nuclei without atypia or mitotic activity. it has a striking predilection for the upper lip. Although a rare salivary gland tumor overall, they are outnumbered only by pleomorphic adenomas at this specific site.
Honey is an ancient delicacy. It has been around for centuries as both a sweetener and a healing agent. There are over 4,000 years of recorded use of honey as a medicinal agent.
thoughts and musings
Marginal zone lymphomas. 1. Nodal = proliferation of monocyoid B cells in a diffuse, sinusoidal or interfollicular pattern, permeates the follicles. Look for Dutcher bodies (ND- nuclear). 2. MALT = small round lymphs with lots of pale cytoplasm and indented nuclei (monocytoid B cells), plasma cells (ND), and lymphoepithelial lesions. The plasma cells are actually monoclonal! Also can see regular old reactive follicles, don't be fooled that
If you are a person that struggles with food sensitivities, allergies, autoimmune disease, inflammatory bowel disease or leaky gut syndrome, then there is a chance that a class of vegetables called Nightshades could be contributing to your health condition.
Fibromyalgia is a central nervous system illness and is also referred to as a syndrome rather than a disease. Unlike a disease, which is a
Did you know that there are five different types of white blood cells? They can be remembered with the mnemonic "Never Let Monkeys Eat Bananas", though they are not in that order in this image. From left to right, this is a neutrophil, monocyte, basophil, lymphocyte, and eosinophil. The light pink dots around them are red blood cells.
Vintage Waverly pattern has all the charm of a country cottage. Small Red, Blue and Pink flowers with Yellow accents are intertwined on Green vining stems arrayed against a White background. This is an all-over pattern but since the flowers are small scale, there is lots of white ~ it is not overwhelming.
Creating the PowderSurfer: What Jeremy Jensen and his company created is called a powdersurfer. These snow riding boards are somewhat related to snowboarding but unique. Basically these boards have a similar look and construction to a skateboard deck (horizontally laminated wood) but are wider and longer with a foam type grip tape. There are no bindings and no edges so the riding is like surfing on (powder) snow. no bindings + powder = FUN! #snow #surfing
Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing. These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator
Sadly, so many do. There are those that think because they wear lovely clothes they are somehow better people than most and then there are others who are automatically threatened by a person who looks very elegant and call that person a snob. It works both ways. In truth, elegance comes from within and has nothing to do with clothing.
Endosalpingiosis! Cilia! numerous chronic inflammatory cells and bland-appearing mesothelial cells. Rare cohesive epithelial fragments are present, and at high power these cells have enlarged nuclei, multiple conspicuous nucleoli, and cilia.
Cashmere Collection Flat Cross Body - RaisinThis is a cross body bag that has a cell phone or black berry case on the front. Next to it there is a seven inch zippered pocket that goes three inches towards the bottom of the bag. Above both of those pockets there is a nine inch open pocket that has a depth of nine inches. The main compartment of this bag has a gusseted zipper so that the bag opens wide to find things that are inside the compartment. Inside the main compartment you will find an eight inch zippered wall pocket, key ring, two open pockets, and two pen loops. On the back of this bag there is an eleven inch zippered pocket that goes ten inches
It's said that there are over 600 seed varieties of heirloom tomatoes. A whole lot of flavor to cook with this spring!
In the Garden
I hate this with a passion. HE HAS A FRICKEN NAME! AND THERE IS THREE OTHERS! The faces at the bottom are perf
Turmeric kills cancer cells, is a natural pain reliever and can slow down Alzheimer's disease.
Style for style
THIS SATURATED FAT IMPROVES ALZHEIMER'S DISEASE SYMPTOMS. A new study in Alzheimer's disease (AD) patients using dietary supplementation with a unique saturated fat has confirmed earlier research that a non-drug based approach can stabilize and even improve a degenerative disease whose symptoms are usually managed with drugs as opposed to being cured. Learn about the brain benefits of coconut oil.
knowing how to be solitary is central... When we can be alone, we can be with others without using them as a means of escape. -bell hooks
DID YOU KNOW...the dirtiest part of the body is the mouth. Yikes! The back of the tongue is a breeding ground for pathogenic microorganisms. There are studies that link oral health with general health, including links to cancer and heart disease. Enter OIL PULLING!
Ball gown, British, ca. 1885. Bodice & skirt are moir� silk overlaid & trimmed w/machine-made lace. Bodice is heavily boned & very close-fitting; has narrow waist and is laced at back to resemble a corset. The deep point of the bodice gracefully curves over the back of the skirt. Neckline is low and square at the front and rounded at the back and trimmed with a fall of lace. Lined w/silk, cotton, & whalebone strips. Made for May Primrose