DARIER's Disease = This solitary keratotic papule has a somewhat endophytic growth pattern, with a central plug of keratin. There is both acantholysis and dyskeratosis. There is suprabasal acantholysis over a papillomatous superficial dermis. Above the suprabasal acantholysis, there are large, eosinophilic, rounded suprabasal cells with perinuclear halos (Corps Ronds). Above these are small dark cells with pyknotic nuclei and a millet-seed-like by bernadine
bernadine
bernadine DARIER's Disease = This solitary keratotic papule has a somewhat endophytic growth pattern, with a central plug of keratin. There is both acantholysis and dyskeratosis. There is suprabasal acantholysis over a papillomatous superficial dermis. Above the suprabasal acantholysis, there are large, eosinophilic, rounded suprabasal cells with perinuclear halos (Corps Ronds). Above these are small dark cells with pyknotic nuclei and a millet-seed-like
Getting
Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini
Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam)
Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm)
Signet ring cells or intercellular glandular lumens by rochelle
rochelle
rochelle Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam) Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm) Signet ring cells or intercellular glandular lumens
bargain
Epithelioid sarcoma. The tumor lesion on low power has the morphology of a palisaded necrotizing granuloma. There appears to be central collagenous necrobiosis, and the lesional cells simulate histiocytes surrounding this necrobiosis. However, the surrounding cells demonstrate fairly prominent nucleoli, and mitotic figures are evident. These cells label for both cytokeratin (shown below) and CD34, establishing the diagnosis of epithelioid sarcoma. by lacey
lacey
lacey Epithelioid sarcoma. The tumor lesion on low power has the morphology of a palisaded necrotizing granuloma. There appears to be central collagenous necrobiosis, and the lesional cells simulate histiocytes surrounding this necrobiosis. However, the surrounding cells demonstrate fairly prominent nucleoli, and mitotic figures are evident. These cells label for both cytokeratin (shown below) and CD34, establishing the diagnosis of epithelioid sarcoma.
Favorites
Hairy cell leukemia. Never in nodes. BLOOD: mimics aplastic anemia (has characteristic MONOCYTOPENIA and neutropenia- reason you would die from it). Very few neoplastic cells in blood. DO NOT DIAGNOSE if there are monocytes. Classic cell morphology = bigger, with nucleus 2x size of normal one and the cell size is very uniform, no transformed cells. Nuclei can be round, oval, RENIFORM, or bilobed. Chromatin is very distinct ground glass and NO by carolina
carolina
carolina Hairy cell leukemia. Never in nodes. BLOOD: mimics aplastic anemia (has characteristic MONOCYTOPENIA and neutropenia- reason you would die from it). Very few neoplastic cells in blood. DO NOT DIAGNOSE if there are monocytes. Classic cell morphology = bigger, with nucleus 2x size of normal one and the cell size is very uniform, no transformed cells. Nuclei can be round, oval, RENIFORM, or bilobed. Chromatin is very distinct ground glass and NO
Favorites
Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling  feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing.  These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator into thinking it is actually a large predatory owl. by proteamundi
proteamundi
proteamundi Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing. These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator into thinking it is actually a large predatory owl.
Favorites
Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it difficult to breathe. There are two main forms of COPD: Chronic bronchitis, which involves a long-term cough with mucus Emphysema, which involves destruction of the lungs over time Most people with COPD have a combination of both conditions. by sybil
sybil
sybil Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it difficult to breathe. There are two main forms of COPD: Chronic bronchitis, which involves a long-term cough with mucus Emphysema, which involves destruction of the lungs over time Most people with COPD have a combination of both conditions.
Natural Elements
canalicular adenoma on lip. it is characterized by double columns of cells forming interconnecting channels that course through a loose myxoid stroma. The cells forming the channels have columnar, uniformly aligned nuclei without atypia or mitotic activity. it has a striking predilection for the upper lip. Although a rare salivary gland tumor overall, they are outnumbered only by pleomorphic adenomas at this specific site. by graciela
graciela
graciela canalicular adenoma on lip. it is characterized by double columns of cells forming interconnecting channels that course through a loose myxoid stroma. The cells forming the channels have columnar, uniformly aligned nuclei without atypia or mitotic activity. it has a striking predilection for the upper lip. Although a rare salivary gland tumor overall, they are outnumbered only by pleomorphic adenomas at this specific site.
Spend
PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei. by tamera
tamera
tamera PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei.
Nobody Does it Better than Nature
Honey is an ancient delicacy. It has been around for centuries as both a sweetener and a healing agent. There are over 4,000 years of recorded use of honey as a medicinal agent. by lucia
lucia
lucia Honey is an ancient delicacy. It has been around for centuries as both a sweetener and a healing agent. There are over 4,000 years of recorded use of honey as a medicinal agent.
thoughts and musings
Marginal zone lymphomas. 1. Nodal = proliferation of monocyoid B cells in a diffuse, sinusoidal or interfollicular pattern, permeates the follicles.  Look for Dutcher bodies (ND- nuclear). 2. MALT = small round lymphs with lots of pale cytoplasm and indented nuclei (monocytoid B cells), plasma cells (ND), and lymphoepithelial lesions. The plasma cells are actually monoclonal!  Also can see regular old reactive follicles, don't be fooled that by dee
dee
dee Marginal zone lymphomas. 1. Nodal = proliferation of monocyoid B cells in a diffuse, sinusoidal or interfollicular pattern, permeates the follicles. Look for Dutcher bodies (ND- nuclear). 2. MALT = small round lymphs with lots of pale cytoplasm and indented nuclei (monocytoid B cells), plasma cells (ND), and lymphoepithelial lesions. The plasma cells are actually monoclonal! Also can see regular old reactive follicles, don't be fooled that
Favorites
Ashton Linen ToteEvery Canyon Outback Ashton Linen Tote will have a slightly different look. The tie-dyed linen is paired with genuine leather. The bag has a large main compartment. There are two zippered pockets and a cell phone pocket for your small valuables. There is a front slash pocket with snaps to hold a jacket or yoga mat. by deeshop
deeshop
deeshop Ashton Linen ToteEvery Canyon Outback Ashton Linen Tote will have a slightly different look. The tie-dyed linen is paired with genuine leather. The bag has a large main compartment. There are two zippered pockets and a cell phone pocket for your small valuables. There is a front slash pocket with snaps to hold a jacket or yoga mat.
Hot sellers
Bell P59 Airacomet (below) - America's first jet plane offered only a small advantage over conventional piston-engined fighters and was confined to the training role.  Above is the P-63 Kingcobra ... neither plane was outstanding, but both were unique. by elizabeth
elizabeth
elizabeth Bell P59 Airacomet (below) - America's first jet plane offered only a small advantage over conventional piston-engined fighters and was confined to the training role. Above is the P-63 Kingcobra ... neither plane was outstanding, but both were unique.
Favorites
If you are a person that struggles with food sensitivities, allergies, autoimmune disease, inflammatory bowel disease or leaky gut syndrome, then there is a chance that a class of vegetables called Nightshades could be contributing to your health condition. by AislingH
AislingH
AislingH If you are a person that struggles with food sensitivities, allergies, autoimmune disease, inflammatory bowel disease or leaky gut syndrome, then there is a chance that a class of vegetables called Nightshades could be contributing to your health condition.
Favorites
Fibromyalgia is a central nervous system illness and is also referred to as a syndrome rather than a disease. Unlike a disease, which is a by yvette
yvette
yvette Fibromyalgia is a central nervous system illness and is also referred to as a syndrome rather than a disease. Unlike a disease, which is a
parties
Did you know that there are five different types of white blood cells?  They can be remembered with the mnemonic "Never Let Monkeys Eat Bananas", though they are not in that order in this image.  From left to right, this is a neutrophil, monocyte, basophil, lymphocyte, and eosinophil.  The light pink dots around them are red blood cells. by Graybird
Graybird
Graybird Did you know that there are five different types of white blood cells? They can be remembered with the mnemonic "Never Let Monkeys Eat Bananas", though they are not in that order in this image. From left to right, this is a neutrophil, monocyte, basophil, lymphocyte, and eosinophil. The light pink dots around them are red blood cells.
Favorites
Vintage Waverly pattern has all the charm of a country cottage. Small Red, Blue and Pink flowers with Yellow accents are intertwined on Green vining stems arrayed against a White background. This is an all-over pattern but since the flowers are small scale, there is lots of white ~ it is not overwhelming. by marcia
marcia
marcia Vintage Waverly pattern has all the charm of a country cottage. Small Red, Blue and Pink flowers with Yellow accents are intertwined on Green vining stems arrayed against a White background. This is an all-over pattern but since the flowers are small scale, there is lots of white ~ it is not overwhelming.
Favorites
Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling  feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing.  These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator by ophelia
ophelia
ophelia Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing. These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator
butterflies
Cashmere Collection Flat Cross Body - RaisinThis is a cross body bag that has a cell phone or black berry case on the front. Next to it there is a seven inch zippered pocket that goes three inches towards the bottom of the bag. Above both of those pockets there is a nine inch open pocket that has a depth of nine inches. The main compartment of this bag has a gusseted zipper so that the bag opens wide to find things that are inside the compartment. Inside the main compartment you will find an eight inch zippered wall pocket, key ring, two open pockets, and two pen loops. On the back of this bag there is an eleven inch zippered pocket that goes ten inches by deeshop
deeshop
deeshop Cashmere Collection Flat Cross Body - RaisinThis is a cross body bag that has a cell phone or black berry case on the front. Next to it there is a seven inch zippered pocket that goes three inches towards the bottom of the bag. Above both of those pockets there is a nine inch open pocket that has a depth of nine inches. The main compartment of this bag has a gusseted zipper so that the bag opens wide to find things that are inside the compartment. Inside the main compartment you will find an eight inch zippered wall pocket, key ring, two open pockets, and two pen loops. On the back of this bag there is an eleven inch zippered pocket that goes ten inches
Hot sellers
Scrotum. Granular cell tumor. S100 positive, CD68 positive, inhibin positive. Lysosomes on EM. uvenile xanthogranuloma features histiocytic cells which merge with those with features of Touton-like giant cells. This lesion labels for CD68, but not for S100 or CD1a. Langerhans histiocytosis is composed of cells with more reniform nuclei, and the lesional cells label for CD1a. by carolina
carolina
carolina Scrotum. Granular cell tumor. S100 positive, CD68 positive, inhibin positive. Lysosomes on EM. uvenile xanthogranuloma features histiocytic cells which merge with those with features of Touton-like giant cells. This lesion labels for CD68, but not for S100 or CD1a. Langerhans histiocytosis is composed of cells with more reniform nuclei, and the lesional cells label for CD1a.
Favorites
Creating the PowderSurfer:  What Jeremy Jensen and his company created is called a powdersurfer. These snow riding boards are somewhat related to snowboarding but unique. Basically these boards have a similar look and construction to a skateboard deck (horizontally laminated wood) but are wider and longer with a foam type grip tape. There are no bindings and no edges so the riding is like surfing on (powder) snow.  no bindings + powder = FUN!  #snow #surfing by jane
jane
jane Creating the PowderSurfer: What Jeremy Jensen and his company created is called a powdersurfer. These snow riding boards are somewhat related to snowboarding but unique. Basically these boards have a similar look and construction to a skateboard deck (horizontally laminated wood) but are wider and longer with a foam type grip tape. There are no bindings and no edges so the riding is like surfing on (powder) snow. no bindings + powder = FUN! #snow #surfing
Favorites
Endosalpingiosis!  Cilia!  numerous chronic inflammatory cells and bland-appearing mesothelial cells. Rare cohesive epithelial fragments are present, and at high power these cells have enlarged nuclei, multiple conspicuous nucleoli, and cilia. by graciela
graciela
graciela Endosalpingiosis! Cilia! numerous chronic inflammatory cells and bland-appearing mesothelial cells. Rare cohesive epithelial fragments are present, and at high power these cells have enlarged nuclei, multiple conspicuous nucleoli, and cilia.
Spend
Sadly, so many do. There are those that think because they wear lovely clothes they are somehow better people than most and then there are others who are automatically threatened by a person who looks very elegant and call that person a snob. It works both ways. In truth, elegance comes from within and has nothing to do with clothing. by marialeal
marialeal
marialeal Sadly, so many do. There are those that think because they wear lovely clothes they are somehow better people than most and then there are others who are automatically threatened by a person who looks very elegant and call that person a snob. It works both ways. In truth, elegance comes from within and has nothing to do with clothing.
letter
I hate this with a passion. HE HAS A FRICKEN NAME! AND THERE IS THREE OTHERS! The faces at the bottom are perf by rebecca2
rebecca2
rebecca2 I hate this with a passion. HE HAS A FRICKEN NAME! AND THERE IS THREE OTHERS! The faces at the bottom are perf
Favorites
ellulite is fatty cells that build on the skin to form a somewhat like dimpled appearance by beckyjane
beckyjane
beckyjane ellulite is fatty cells that build on the skin to form a somewhat like dimpled appearance
HEALTH&WELLNES
Buy 25 Plastic Seed Starting Trays - Each Tray Has 72 Cells ~ Cells Are 1.44 ' Round X 2.38 ' Deep. Great Propagation... by Kitchen8
Kitchen8
Kitchen8 Buy 25 Plastic Seed Starting Trays - Each Tray Has 72 Cells ~ Cells Are 1.44 ' Round X 2.38 ' Deep. Great Propagation...
Buy kitchen Product Cheap Price.
Ball gown, British, ca. 1885. Bodice & skirt are moir� silk overlaid & trimmed w/machine-made lace. Bodice is heavily boned & very close-fitting; has narrow waist and is laced at back to resemble a corset. The deep point of the bodice gracefully curves over the back of the skirt. Neckline is low and square at the front and rounded at the back and trimmed with a fall of lace. Lined w/silk, cotton, & whalebone strips. Made for May Primrose by oldrose
oldrose
oldrose Ball gown, British, ca. 1885. Bodice & skirt are moir� silk overlaid & trimmed w/machine-made lace. Bodice is heavily boned & very close-fitting; has narrow waist and is laced at back to resemble a corset. The deep point of the bodice gracefully curves over the back of the skirt. Neckline is low and square at the front and rounded at the back and trimmed with a fall of lace. Lined w/silk, cotton, & whalebone strips. Made for May Primrose
Pioneer
THIS SATURATED FAT IMPROVES ALZHEIMER'S DISEASE SYMPTOMS. A new study in Alzheimer's disease (AD) patients using dietary supplementation with a unique saturated fat has confirmed earlier research that a non-drug based approach can stabilize and even improve a degenerative disease whose symptoms are usually managed with drugs as opposed to being cured. Learn about the brain benefits of coconut oil. by katy
katy
katy THIS SATURATED FAT IMPROVES ALZHEIMER'S DISEASE SYMPTOMS. A new study in Alzheimer's disease (AD) patients using dietary supplementation with a unique saturated fat has confirmed earlier research that a non-drug based approach can stabilize and even improve a degenerative disease whose symptoms are usually managed with drugs as opposed to being cured. Learn about the brain benefits of coconut oil.
Favorites
Fight high cholesterol, heart disease and diabetes with flax seed. by lorene
lorene
lorene Fight high cholesterol, heart disease and diabetes with flax seed.
Books Worth Reading
Artist and curator Katarina Wong reminds us that part of the joy of creation is sharing it with others. There is something so special for both the viewer and the artist when art is shared. That’s why she created MADE, a company that helps artists’ art find homes. Our lives are enhanced when we share it with art. How has viewing or having an artwork positively impacted your life? #Artistthink #art #artists #creative #creativity #arts #artistsofinstagram #artistsoninstagram #artstagram #quote.... by carolyn
carolyn
carolyn Artist and curator Katarina Wong reminds us that part of the joy of creation is sharing it with others. There is something so special for both the viewer and the artist when art is shared. That’s why she created MADE, a company that helps artists’ art find homes. Our lives are enhanced when we share it with art. How has viewing or having an artwork positively impacted your life? #Artistthink #art #artists #creative #creativity #arts #artistsofinstagram #artistsoninstagram #artstagram #quote....
Favorites
knowing how to be solitary is central... When we can be alone, we can be with others without using them as a means of escape. -bell hooks by ollie
ollie
ollie knowing how to be solitary is central... When we can be alone, we can be with others without using them as a means of escape. -bell hooks
Favorites
It's said that there are over 600 seed varieties of heirloom tomatoes. A whole lot of flavor to cook with this spring! by jana
jana
jana It's said that there are over 600 seed varieties of heirloom tomatoes. A whole lot of flavor to cook with this spring!
In the Garden