DARIER's Disease = This solitary keratotic papule has a somewhat endophytic growth pattern, with a central plug of keratin. There is both acantholysis and dyskeratosis. There is suprabasal acantholysis over a papillomatous superficial dermis. Above the suprabasal acantholysis, there are large, eosinophilic, rounded suprabasal cells with perinuclear halos (Corps Ronds). Above these are small dark cells with pyknotic nuclei and a millet-seed-like by bernadine
bernadine
bernadine DARIER's Disease = This solitary keratotic papule has a somewhat endophytic growth pattern, with a central plug of keratin. There is both acantholysis and dyskeratosis. There is suprabasal acantholysis over a papillomatous superficial dermis. Above the suprabasal acantholysis, there are large, eosinophilic, rounded suprabasal cells with perinuclear halos (Corps Ronds). Above these are small dark cells with pyknotic nuclei and a millet-seed-like
Getting
Epithelioid sarcoma. The tumor lesion on low power has the morphology of a palisaded necrotizing granuloma. There appears to be central collagenous necrobiosis, and the lesional cells simulate histiocytes surrounding this necrobiosis. However, the surrounding cells demonstrate fairly prominent nucleoli, and mitotic figures are evident. These cells label for both cytokeratin (shown below) and CD34, establishing the diagnosis of epithelioid sarcoma. by lacey
lacey
lacey Epithelioid sarcoma. The tumor lesion on low power has the morphology of a palisaded necrotizing granuloma. There appears to be central collagenous necrobiosis, and the lesional cells simulate histiocytes surrounding this necrobiosis. However, the surrounding cells demonstrate fairly prominent nucleoli, and mitotic figures are evident. These cells label for both cytokeratin (shown below) and CD34, establishing the diagnosis of epithelioid sarcoma.
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Hairy cell leukemia. Never in nodes. BLOOD: mimics aplastic anemia (has characteristic MONOCYTOPENIA and neutropenia- reason you would die from it). Very few neoplastic cells in blood. DO NOT DIAGNOSE if there are monocytes. Classic cell morphology = bigger, with nucleus 2x size of normal one and the cell size is very uniform, no transformed cells. Nuclei can be round, oval, RENIFORM, or bilobed. Chromatin is very distinct ground glass and NO by carolina
carolina
carolina Hairy cell leukemia. Never in nodes. BLOOD: mimics aplastic anemia (has characteristic MONOCYTOPENIA and neutropenia- reason you would die from it). Very few neoplastic cells in blood. DO NOT DIAGNOSE if there are monocytes. Classic cell morphology = bigger, with nucleus 2x size of normal one and the cell size is very uniform, no transformed cells. Nuclei can be round, oval, RENIFORM, or bilobed. Chromatin is very distinct ground glass and NO
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Honey is an ancient delicacy. It has been around for centuries as both a sweetener and a healing agent. There are over 4,000 years of recorded use of honey as a medicinal agent. by lucia
lucia
lucia Honey is an ancient delicacy. It has been around for centuries as both a sweetener and a healing agent. There are over 4,000 years of recorded use of honey as a medicinal agent.
thoughts and musings
Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini
Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam)
Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm)
Signet ring cells or intercellular glandular lumens by rochelle
rochelle
rochelle Pancreatic ductal adeno. Flat sheets of cells, three dimensional balls, and microacini Columnar cells with delicate cytoplasm and polar nuclei (basal nuclei, apical cytoplsam) Open chromatin with prominent central single nucleolus (versus squamous cell carcinoma with nuclei with dense chromatin and several small nucleoli, and dense cytoplasm) Signet ring cells or intercellular glandular lumens
bargain
Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it difficult to breathe. There are two main forms of COPD: Chronic bronchitis, which involves a long-term cough with mucus Emphysema, which involves destruction of the lungs over time Most people with COPD have a combination of both conditions. by sybil
sybil
sybil Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it difficult to breathe. There are two main forms of COPD: Chronic bronchitis, which involves a long-term cough with mucus Emphysema, which involves destruction of the lungs over time Most people with COPD have a combination of both conditions.
Natural Elements
Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling  feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing.  These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator into thinking it is actually a large predatory owl. by proteamundi
proteamundi
proteamundi Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing. These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator into thinking it is actually a large predatory owl.
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canalicular adenoma on lip. it is characterized by double columns of cells forming interconnecting channels that course through a loose myxoid stroma. The cells forming the channels have columnar, uniformly aligned nuclei without atypia or mitotic activity. it has a striking predilection for the upper lip. Although a rare salivary gland tumor overall, they are outnumbered only by pleomorphic adenomas at this specific site. by graciela
graciela
graciela canalicular adenoma on lip. it is characterized by double columns of cells forming interconnecting channels that course through a loose myxoid stroma. The cells forming the channels have columnar, uniformly aligned nuclei without atypia or mitotic activity. it has a striking predilection for the upper lip. Although a rare salivary gland tumor overall, they are outnumbered only by pleomorphic adenomas at this specific site.
Spend
PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei. by tamera
tamera
tamera PVNS. Mononuclear cells and giant cells. Plasmacytoid nuclei.
Nobody Does it Better than Nature
Marginal zone lymphomas. 1. Nodal = proliferation of monocyoid B cells in a diffuse, sinusoidal or interfollicular pattern, permeates the follicles.  Look for Dutcher bodies (ND- nuclear). 2. MALT = small round lymphs with lots of pale cytoplasm and indented nuclei (monocytoid B cells), plasma cells (ND), and lymphoepithelial lesions. The plasma cells are actually monoclonal!  Also can see regular old reactive follicles, don't be fooled that by dee
dee
dee Marginal zone lymphomas. 1. Nodal = proliferation of monocyoid B cells in a diffuse, sinusoidal or interfollicular pattern, permeates the follicles. Look for Dutcher bodies (ND- nuclear). 2. MALT = small round lymphs with lots of pale cytoplasm and indented nuclei (monocytoid B cells), plasma cells (ND), and lymphoepithelial lesions. The plasma cells are actually monoclonal! Also can see regular old reactive follicles, don't be fooled that
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Cauliflower rice has become a classic low-carb dish and there are lots of cauliflower rice recipes out there, but this recipe for The Best Easy Cauliflower Rice with Garlic and Green Onion is the one I make over and over! [found on KalynsKitchen.com] by Leona Hines
Leona Hines
Leona Hines Cauliflower rice has become a classic low-carb dish and there are lots of cauliflower rice recipes out there, but this recipe for The Best Easy Cauliflower Rice with Garlic and Green Onion is the one I make over and over! [found on KalynsKitchen.com]
CAULIFLOWER AND RICE
This is a really well thought out loft conversion project. We love the simple folded steel shading device around the dormer windows and how the architect has used matching roof tiles to seamlessly integrate the new addition with the existing roof. The stand-out feature of this design, however, is that window that folds up and over to become a skylight, bringing both a view of the trees beyond and the sky above into the bedroom space. by josefina
josefina
josefina This is a really well thought out loft conversion project. We love the simple folded steel shading device around the dormer windows and how the architect has used matching roof tiles to seamlessly integrate the new addition with the existing roof. The stand-out feature of this design, however, is that window that folds up and over to become a skylight, bringing both a view of the trees beyond and the sky above into the bedroom space.
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If you are a person that struggles with food sensitivities, allergies, autoimmune disease, inflammatory bowel disease or leaky gut syndrome, then there is a chance that a class of vegetables called Nightshades could be contributing to your health condition. by AislingH
AislingH
AislingH If you are a person that struggles with food sensitivities, allergies, autoimmune disease, inflammatory bowel disease or leaky gut syndrome, then there is a chance that a class of vegetables called Nightshades could be contributing to your health condition.
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JD Salinger wrote, “There are still a few men who love desperately.”…of which I am one.  I am not interested in the common, the shallow, the ordinary, nor the superficial.  I crave the kind of love that is rare, exceptional, and perseveres against all odds.   The kind of love that heals a scarred heart…and completes a searching soul with its mate.  This is what you give me... by imogene
imogene
imogene JD Salinger wrote, “There are still a few men who love desperately.”…of which I am one. I am not interested in the common, the shallow, the ordinary, nor the superficial. I crave the kind of love that is rare, exceptional, and perseveres against all odds. The kind of love that heals a scarred heart…and completes a searching soul with its mate. This is what you give me...
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This mother of a boy with autism and celiac disease has dished up a whole blog worth of recipes that are GF/CF by randi
randi
randi This mother of a boy with autism and celiac disease has dished up a whole blog worth of recipes that are GF/CF
yummy & healthy
Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks itself. The pattern of joints affected is usually symmetrical, involves the hands and other joints and is worse in the morning. Rheumatoid arthritis is also a systemic disease, involving other body organs, whereas osteoarthritis is limited to the joints. Over time, both forms of arthritis can be crippling. by cristina
cristina
cristina Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks itself. The pattern of joints affected is usually symmetrical, involves the hands and other joints and is worse in the morning. Rheumatoid arthritis is also a systemic disease, involving other body organs, whereas osteoarthritis is limited to the joints. Over time, both forms of arthritis can be crippling.
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Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling  feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing.  These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator by ophelia
ophelia
ophelia Forest Giant Owl Butterfly -- A group of South & Central America butterflies. The underside of the wings look nothing like the upper wings. The undersides are brown with markings somewhat resembling feathers, and there is a large prominent black spot with a bright yellow ring around it on each lower wing. These spots look like eyes. When the butterfly is threatened, it assumes an upside down pose displaying eyespots. This startles a predator
butterflies
ellulite is fatty cells that build on the skin to form a somewhat like dimpled appearance by beckyjane
beckyjane
beckyjane ellulite is fatty cells that build on the skin to form a somewhat like dimpled appearance
HEALTH&WELLNES
There are around 4000 to 6000 of these tiny creatures left in the world because of cave destruction/tourism, and even agriculture growth destroying homes. It is unique, both for its tiny size (just a few inches) and its pale coloring. (great site) Honduran Ghost Bat by Hercio Dias
Hercio Dias
Hercio Dias There are around 4000 to 6000 of these tiny creatures left in the world because of cave destruction/tourism, and even agriculture growth destroying homes. It is unique, both for its tiny size (just a few inches) and its pale coloring. (great site) Honduran Ghost Bat
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I hate this with a passion. HE HAS A FRICKEN NAME! AND THERE IS THREE OTHERS! The faces at the bottom are perf by rebecca2
rebecca2
rebecca2 I hate this with a passion. HE HAS A FRICKEN NAME! AND THERE IS THREE OTHERS! The faces at the bottom are perf
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Endosalpingiosis!  Cilia!  numerous chronic inflammatory cells and bland-appearing mesothelial cells. Rare cohesive epithelial fragments are present, and at high power these cells have enlarged nuclei, multiple conspicuous nucleoli, and cilia. by graciela
graciela
graciela Endosalpingiosis! Cilia! numerous chronic inflammatory cells and bland-appearing mesothelial cells. Rare cohesive epithelial fragments are present, and at high power these cells have enlarged nuclei, multiple conspicuous nucleoli, and cilia.
Spend
Fight high cholesterol, heart disease and diabetes with flax seed. by lorene
lorene
lorene Fight high cholesterol, heart disease and diabetes with flax seed.
Books Worth Reading
THIS SATURATED FAT IMPROVES ALZHEIMER'S DISEASE SYMPTOMS. A new study in Alzheimer's disease (AD) patients using dietary supplementation with a unique saturated fat has confirmed earlier research that a non-drug based approach can stabilize and even improve a degenerative disease whose symptoms are usually managed with drugs as opposed to being cured. Learn about the brain benefits of coconut oil. by katy
katy
katy THIS SATURATED FAT IMPROVES ALZHEIMER'S DISEASE SYMPTOMS. A new study in Alzheimer's disease (AD) patients using dietary supplementation with a unique saturated fat has confirmed earlier research that a non-drug based approach can stabilize and even improve a degenerative disease whose symptoms are usually managed with drugs as opposed to being cured. Learn about the brain benefits of coconut oil.
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Aquarius and Capricorn are both there. by kayla
kayla
kayla Aquarius and Capricorn are both there.
astronomy
Responding to continued growth, the Texas A University Corps of Cadets will reactivate Friday (Jan. 11) two of its traditional units, including the one in which Gov. Perry and Texas A System Chancellor John Sharp served. Gov. Perry and Sharp, both 1972 graduates, are scheduled to attend the 10 a.m. activation ceremonies. by hallie
hallie
hallie Responding to continued growth, the Texas A University Corps of Cadets will reactivate Friday (Jan. 11) two of its traditional units, including the one in which Gov. Perry and Texas A System Chancellor John Sharp served. Gov. Perry and Sharp, both 1972 graduates, are scheduled to attend the 10 a.m. activation ceremonies.
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Artist and curator Katarina Wong reminds us that part of the joy of creation is sharing it with others. There is something so special for both the viewer and the artist when art is shared. That’s why she created MADE, a company that helps artists’ art find homes. Our lives are enhanced when we share it with art. How has viewing or having an artwork positively impacted your life? #Artistthink #art #artists #creative #creativity #arts #artistsofinstagram #artistsoninstagram #artstagram #quote.... by carolyn
carolyn
carolyn Artist and curator Katarina Wong reminds us that part of the joy of creation is sharing it with others. There is something so special for both the viewer and the artist when art is shared. That’s why she created MADE, a company that helps artists’ art find homes. Our lives are enhanced when we share it with art. How has viewing or having an artwork positively impacted your life? #Artistthink #art #artists #creative #creativity #arts #artistsofinstagram #artistsoninstagram #artstagram #quote....
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knowing how to be solitary is central... When we can be alone, we can be with others without using them as a means of escape. -bell hooks by ollie
ollie
ollie knowing how to be solitary is central... When we can be alone, we can be with others without using them as a means of escape. -bell hooks
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Small left foot ankle boot with a rounded toe and missing sole. The uppers are one-piece with an angled seam in the inner side and a front fastening of two buckles. The throat has been further cut down the vamp towards the toe and the vamp is also cut horizontally across the toes. The heel stiffener is still in situ. The throat has stitch holes for the tongue insert. There is a small strap loop below where the buckle would have been for the strap fastening to be tucked in. 15th century, London by chrystal
chrystal
chrystal Small left foot ankle boot with a rounded toe and missing sole. The uppers are one-piece with an angled seam in the inner side and a front fastening of two buckles. The throat has been further cut down the vamp towards the toe and the vamp is also cut horizontally across the toes. The heel stiffener is still in situ. The throat has stitch holes for the tongue insert. There is a small strap loop below where the buckle would have been for the strap fastening to be tucked in. 15th century, London
Fashion - Vintage
5 Best Yoga Poses To Encourage And Energize Cancer Patients : Cancer, in its myriad forms, constitutes no less than a battle. It is a battle with both the disease as well as its treatment. #Yoga #YogaPoses by anita
anita
anita 5 Best Yoga Poses To Encourage And Energize Cancer Patients : Cancer, in its myriad forms, constitutes no less than a battle. It is a battle with both the disease as well as its treatment. #Yoga #YogaPoses
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Turmeric kills cancer cells, is a natural pain reliever and can slow down Alzheimer's disease. by sherrie
sherrie
sherrie Turmeric kills cancer cells, is a natural pain reliever and can slow down Alzheimer's disease.
Style for style
Its pectin has a detoxifying effect & can help with colitis, IBS & other digestive disorders. The triterpenoids in apple peel have potent anti-growth activity against cancer cells in the liver, colon & breast. Eating apples may reduce the risk of metabolic syndrome, linked to heart disease & diabetes. Increased production of acetylcholine that helps memory & lowers risk of Alzheimer's has been linked to its juice. Quercetin, an antioxidant in by DeniseGaia
DeniseGaia
DeniseGaia Its pectin has a detoxifying effect & can help with colitis, IBS & other digestive disorders. The triterpenoids in apple peel have potent anti-growth activity against cancer cells in the liver, colon & breast. Eating apples may reduce the risk of metabolic syndrome, linked to heart disease & diabetes. Increased production of acetylcholine that helps memory & lowers risk of Alzheimer's has been linked to its juice. Quercetin, an antioxidant in
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